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health, and Balance Point Multivitamin to help fulfill
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Veraferm Supplement Facts |
||
|---|---|---|
| Serving Size: 3 Capsules Servings Per Container: 30 |
||
| Amount Per Serving | Daily Value | |
| Biotin | 500 mcg | 167% |
| Calcium (as Calcium Caprylate 1000 mg) | 120 mg | 12% |
| Golden Seal (Hydrastis canadensis) (root) | 350 mg | * |
| Garlic (Allium sativum) | 500 mg | * |
| Probiotic Blend Fungal Amylase 50 mg Lipase 50 mg Cellulase 50 mg Invertase 50 mg Fungal Lactase 50 mg |
150 mg | * |
| Lactoferrin | 100 mg | * |
| *Daily Value Not Established †At the time of manufacture |
Other Ingredients: Gelatin, Magnesium Stearate, Rice Powder
Daily Dosage: As a dietary supplement, take two capsules in the morning and one capsule in the afternoon with 8 ounces of water. 45-60 days of continuous use is necessary for optimum results.
Veraferm Research:
Caprylic Acid - A unique fatty acid, caprylic acid is usually extracted from plant sources like coconut oil. Older research shows it has antifungal properties (1,2). Empirically, caprylic acid demonstrates clinically effectiveness in treating candidiasis (usually caused by Candida albicans).
Goldenseal (Hydrastis canadensis) - Goldenseal contains constituents like berberine which have demonstrated antimicrobial action against pathogenic bacteria (3). A combination of goldenseal and echinacea has been shown to enhance immune function in animals by increasing production of immunoglobulins (4). Animal research shows that berberine exhibits synergistic effects with amphotericin B against disseminated candidiasis, and can inhibit growth of C. albicans (5). As well, berberine can inhibit production of a lipase enzyme from C. rugosa that assists in colonizing the skin and mucosal surfaces (6).
Garlic (Allium sativa) - A culinary plant, garlic can be used to treat a wide variety of disorders. It has potent antimicrobial effects against bacteria like E. coli, and even antibiotic resistant strains of Staphylococcus aureus (7,8). Garlic extract appears to be effective against C. albicans by inducing oxidative stress (9). The effects of garlic against candida are due to numerous compounds and, for this reason, unlikely to produce resistance (10).
Biotin - This essential vitamin is necessary for skin integrity and plays a role in intermediary metabolism. Deficiency of biotin causes alopecia (hair loss) and a characteristic scaly, red skin rash around body orifices from which C. albicans can be cultured (11).
Probiotics (Lactobacillus acidophilus and Lactobacillus bifidum) - Probiotics are beneficial bacteria (or flora) that line the epithelial tracts (including the GI tract and vagina) and create a healthy microbial balance. Lactobacilli control levels of other microbes including C. albicans through a variety of mechanisms (12). L. acidophilus isolated from patients using oral, vaginal and endocervical swabs demonstrate anti-candida acitivity (13). Oral C. albicans in mice can be eradicated through oral administration of L. acidophilus (14). Candidiasis reduces the gastric output in mice, slowing healing of gastric ulcers and can be attenuated with L. acidophilus supplementation (15).
Lactoferrin - This protein has the unique ability to bind to iron, which pathogenic bacteria and yeast require for growth. In-vitro studies show that lactoferrin can inhibit the growth of C. albicans and C. glabrata, and can block their adhesion to the cell lining of the vaginal tract (16). Lactoferrin appears to work through a separate mechanism than the commonly used anti-fungal drug, fluconazole (17). Oral candidiasis in mice can be treated effectively using lactoferrin, thereby increasing white blood cells and cytokine responses to C. albicans (18).
Veraferm References:
- Wyss O, Ludwig BJ, Joiner RR. The fungistatic and fungicidal action of fatty acids and related compounds. Arch Biochem. 1943;7,415.
- Kabara JJ. Fatty acids and derivatives as antimicrobial agents. In: Kabara JJ, ed. The Pharmacological Effect of Lipids I. Champaign, IL: American Oil Chemists' Society; 1978; 1-14.
- Hwang BY et al. Antimicrobial constituents from goldenseal (the Rhizomes of Hydrastis canadensis) against selected oral pathogens. Planta Med 2003 Jul;69(7):623-7.
- Rehman J et al. Increased production of antigen-specific immunoglobulins G and M following in vivo treatment with the medicinal plants Echinacea angustifolia and Hydrastis canadensis. Immunol Lett 1999 Jun 1;68(2-3):391-5.
- Han Y, Lee JH. Berberine synergy with amphotericin B against disseminated candidiasis in mice. Biol Pharm Bull 2005 Mar;28(3):541-4.
- Grippa E et al. Inhibition of Candida rugosa lipase by berberine and structurally related alkaloids, evaluated by high-performance liquid chromatography. Biosci Biotechnol Biochem 1999 Sep;63(9):1557-62. Grippa E et al.
- Maldonado PD, Chanez-Cardenas ME, Pedraza-Chaverri J. Aged garlic extract, garlic powder extract, S-allylcysteine, diallyl sulfide and diallyl disulfide do not interfere with the antibiotic activity of gentamicin. Phytother Res 2005 Mar;19(3):252-4.
- Dattner AM. From medical herbalism to phytotherapy in dermatology: back to the future. Dermatol Ther 2003;16(2):106-13.
- Lemar KM et al. Allyl alcohol and garlic (Allium sativum) extract produce oxidative stress in Candida albicans. Microbiology 2005 Oct;151(Pt 10):3257-65.
- Lemar KM, Turner MP, Lloyd D. Garlic (Allium sativum) as an anti-Candida agent: a comparison of the efficacy of fresh garlic and freeze-dried extracts. J Appl Microbiol 2002;93(3):398-405.
- Mock DM. Skin manifestations of biotin deficiency. Semin Dermatol 1991 Dec;10(4):296-302. Mock DM.
- Strus M et al. The in vitro activity of vaginal Lactobacillus with probiotic properties against Candida. Infect Dis Obstet Gynecol 2005 Jun;13(2):69-75.
- Fitzsimmons N, Berry DR. Inhibition of Candida albicans by Lactobacillus acidophilus: evidence for the involvement of a peroxidase system. Microbios 1994;80(323):125-33.
- Elahi S et al. Enhanced clearance of Candida albicans from the oral cavities of mice following oral administration of Lactobacillus acidophilus. Clin Exp Immunol 2005 Jul;141(1):29-36.
- Brzozowski T et al. Influence of gastric colonization with Candida albicans on ulcer healing in rats: effect of ranitidine, aspirin and probiotic therapy. Scand J Gastroenterol 2005 Mar;40(3):286-96.
- Naidu AS et al. Activated lactoferrin's ability to inhibit Candida growth and block yeast adhesion to the vaginal epithelial monolayer. J Reprod Med 2004 Nov;49(11):859-66.
- Naidu AS et al. Activated lactoferrin and fluconazole synergism against Candida albicans and Candida glabrata vaginal isolates. J Reprod Med 2004 Oct;49(10):800-7.
- Takakura N et al. Effect of orally administered bovine lactoferrin on the immune response in the oral candidiasis murine model. J Med Microbiol 2004 Jun;53(Pt 6):495-500.
